KinATLAS
TranscriptoNET
PhosphoNET
OncoNET
KinaseNET
DrugKiNET
KiNET-AM
Kinetica Online
Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
|
Home
|
Kinexus
|
Contact
|
Credits
Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
EP300
All Species:
8.48
Human Site:
S973
Identified Species:
15.56
UniProt:
Q09472
Number Species:
12
Phosphosite Substitution
Charge Score:
0.25
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
Q09472
NP_001420.2
2414
264161
S973
A
I
A
E
K
Q
P
S
Q
E
V
K
M
E
A
Chimpanzee
Pan troglodytes
XP_515155
2411
263753
S973
A
I
P
E
K
Q
P
S
Q
E
V
K
M
E
A
Rhesus Macaque
Macaca mulatta
XP_001102844
2414
264251
S973
A
I
P
E
K
Q
P
S
Q
E
V
K
M
E
A
Dog
Lupus familis
XP_851777
2404
260682
M959
Q
T
G
P
E
V
P
M
L
E
V
K
A
E
V
Cat
Felis silvestris
Mouse
Mus musculus
P45481
2441
265456
M995
Q
P
G
P
D
V
P
M
L
E
M
K
T
E
V
Rat
Rattus norvegicus
XP_001076610
2413
263563
E973
P
E
K
Q
P
S
Q
E
V
K
M
E
V
K
M
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
Chicken
Gallus gallus
XP_001233888
2444
267496
Q984
Q
T
A
A
E
Q
Q
Q
P
P
L
Q
E
V
K
Frog
Xenopus laevis
NP_001088637
2428
264402
E999
V
K
V
E
C
K
M
E
E
P
E
V
C
E
N
Zebra Danio
Brachydanio rerio
XP_001332718
2667
289125
E981
V
K
A
K
D
E
E
E
E
E
A
M
E
E
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
NP_524642
3276
340709
D1528
E
A
A
A
R
D
N
D
D
E
T
P
S
P
S
Honey Bee
Apis mellifera
XP_001122031
2606
284119
L1171
M
A
A
I
T
A
A
L
D
R
D
N
S
P
S
Nematode Worm
Caenorhab. elegans
P34545
2056
227161
K818
I
M
N
G
I
V
K
K
E
E
D
P
E
E
S
Sea Urchin
Strong. purpuratus
XP_782558
2635
288594
F1220
A
S
I
K
S
E
P
F
I
K
S
E
P
M
E
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.7
99.2
61
N.A.
58.6
94.1
N.A.
N.A.
85.1
60.4
57
N.A.
36.2
43
31.1
39.5
Protein Similarity:
100
99.7
99.5
72.4
N.A.
69.5
96.1
N.A.
N.A.
89.9
71
65.9
N.A.
46.6
54.9
45.6
51.5
P-Site Identity:
100
93.3
93.3
33.3
N.A.
26.6
0
N.A.
N.A.
13.3
13.3
20
N.A.
13.3
6.6
13.3
13.3
P-Site Similarity:
100
93.3
93.3
40
N.A.
33.3
40
N.A.
N.A.
33.3
26.6
40
N.A.
26.6
13.3
33.3
40
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
31
16
39
16
0
8
8
0
0
0
8
0
8
0
24
% A
% Cys:
0
0
0
0
8
0
0
0
0
0
0
0
8
0
0
% C
% Asp:
0
0
0
0
16
8
0
8
16
0
16
0
0
0
0
% D
% Glu:
8
8
0
31
16
16
8
24
24
62
8
16
24
62
16
% E
% Phe:
0
0
0
0
0
0
0
8
0
0
0
0
0
0
0
% F
% Gly:
0
0
16
8
0
0
0
0
0
0
0
0
0
0
0
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
8
24
8
8
8
0
0
0
8
0
0
0
0
0
0
% I
% Lys:
0
16
8
16
24
8
8
8
0
16
0
39
0
8
8
% K
% Leu:
0
0
0
0
0
0
0
8
16
0
8
0
0
0
0
% L
% Met:
8
8
0
0
0
0
8
16
0
0
16
8
24
8
8
% M
% Asn:
0
0
8
0
0
0
8
0
0
0
0
8
0
0
8
% N
% Pro:
8
8
16
16
8
0
47
0
8
16
0
16
8
16
0
% P
% Gln:
24
0
0
8
0
31
16
8
24
0
0
8
0
0
0
% Q
% Arg:
0
0
0
0
8
0
0
0
0
8
0
0
0
0
0
% R
% Ser:
0
8
0
0
8
8
0
24
0
0
8
0
16
0
24
% S
% Thr:
0
16
0
0
8
0
0
0
0
0
8
0
8
0
0
% T
% Val:
16
0
8
0
0
24
0
0
8
0
31
8
8
8
16
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _